Ask AI: what are the disadvantages of using human umbilical cord mesenchymal stromal cells in cartilage engineering

1. The availability of these cells is limited since they must be harvested from a donor. 2. There is a risk of contamination and immune rejection due to the animal source from which the cells were harvested. 3. The use of these cells may be more expensive than the use of other sources such as for example, adult stem cells. 4. There is the potential risk of introducing unwanted genetic material into the engineered tissue. 5. The presence of other cell types in the mixture of cells used for engineering can interfere with the desired behavior of the engineered tissue.