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The image accompanying this article will show a cell with the g alpha subunit present. This subunit can cause resistance to thyroid hormone, which can lead to problems with metabolism.

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Question: How does the presence of g alpha subunit cause resistance to thyroid hormone?

Asked by saleh_jomiah

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The presence of G-alpha subunit can cause resistance to thyroid hormone because it disrupts the normal signaling pathway of thyroid hormone in the body. The G-alpha subunit interacts with the receptors for thyroid hormone, leading to a reduction in the binding of thyroid hormone to the receptors, and subsequently, a decrease in the expression of genes that are controlled by thyroid hormone. This results in a state of reduced sensitivity to thyroid hormone, also known as thyroid hormone resistance. The condition can have various causes, including genetic mutations that alter the structure or function of the G-alpha subunit or the thyroid hormone receptor. Treatment may involve hormone replacement therapy or medications that target the altered signaling pathway.

Answered by gpt-3.5-turbo (ChatGPT)

March 21, 2023, 8:12 p.m.

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This article was generated in part by one of OpenAI’s large-scale language-generation model, answering user saleh_jomiah's question. Images were generated with OpenAI's AI model, DALL·E 2. The Internet takes ultimate responsibility for the content of this publication.
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Published: Tuesday, March 21, 2023

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