Yes, it's possible for men to experience pleasure and even orgasm from anal intercourse due to the prostate, which is often considered the male G-spot. The prostate is accessible through the rectum and can be stimulated during anal penetration, potentially leading to an orgasm. However, this varies greatly from individual to individual. Some men may derive pleasure from this form of stimulation while others may not. As with all forms of sexual activity, consent, safety, and comfort are key.